Neurotrophins and other growth factors in the regenerative milieu of proximal nerve stump tips

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Neurotrophins and other growth factors in the regenerative milieu of proximal nerve stump tips.

Classic ideas on mechanisms for axon sprouting and nerve regeneration from peripheral nerves suggest that there is a prominent role for neurotrophin support. There has been comparatively less attention towards features of the regenerative process that develop from the proximal nerve trunk without the support of target tissues or the denervated trunk of a peripheral nerve. We studied early (2-14...

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Contribution of the Proximal Nerve Stump in End-to-side Nerve Repair: In a Rat Model

BACKGROUND The aim of this study was to evaluate the contribution of the proximal nerve stump, in end-to-side nerve repair, to functional recovery, by modifying the classic end-to-side neurorrhaphy and suturing the proximal nerve stump to a donor nerve in a rat model of a severed median nerve. METHODS Three experimental groups were studied: a modified end-to-side neurorrhaphy with suturing of...

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ژورنال

عنوان ژورنال: Journal of Anatomy

سال: 2000

ISSN: 0021-8782,1469-7580

DOI: 10.1046/j.1469-7580.2000.19620279.x